Indiana vs. Oregon Prediction, Odds, Picks for 2026 CFP Peach Bowl

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The Oregon Ducks (13-1) are the underdogs, but by less than a touchdown (+3.5), in a College Football Playoff National Championship Semifinal in the Peach Bowl, where they will face the No. 1 Indiana Hoosiers (14-0) in Atlanta, Georgia, starting at 7:30 p.m. ET on January 9, 2026, live on ESPN. The over/under is set at 48.5.

Last time around, the Hoosiers defeated the Alabama Crimson Tide, with 38-3 being the final score. The Ducks’ last game was against the Texas Tech Red Raiders, and they won by a score of 23-0.

Keep up with college football all season on FOX Sports.

[RELATED: Underdogs Yet Favorites, Indiana Football Continues Defying Odds in CFP Run]

Indiana vs. Oregon Game Information & Odds

When: Friday, January 9, 2026 at 7:30 p.m. ET
Location: Mercedes-Benz Stadium in Atlanta, Georgia
TV: ESPN
Streaming: FOX One + ESPN Bundle

Indiana vs. Oregon Prediction

Take the Hoosiers over the Oregon Ducks in tonight’s College Football Playoff semifinal at the Peach Bowl. Indiana’s 14-0 record speaks volumes about its strength, with a defense that has been nearly impenetrable, allowing just 10.3 PPG. Quarterback Fernando Mendoza has been a playmaker, throwing for 3,172 yards and 36 TDs while rushing for 256 yards and six touchdowns.

Oregon has been impressive but has a few injury concerns, as Jordon Davison is out with a broken clavicle and Noah Whittington is listed as questionable. Despite these challenges, the Ducks have shown resilience, having shut out Texas Tech 23-0 in their past game. However, their offense will likely struggle against Indiana’s stout defense, which has held opponents to just 73.7 rushing yards per game.

The Hoosiers have a clear edge, having already beaten the Ducks 30-20 in their previous matchup. With Indiana favored by 3.5 points and the moneyline odds at -183, the Hoosiers are the betting favorites to secure another victory. The predicted final score is Indiana 28, Oregon 23.

Pick ATS: Indiana (-3.5)
Pick OU: Over (48.5)
Prediction: Indiana 28, Oregon 23

Prediction provided by FOX Sports’ Sports AI. Download the FOX Sports App for free access to Sports AI.

Indiana vs. Oregon Betting Insights

Per the spread and over/under, the implied score for the tilt is Hoosiers 26, Ducks 22.
The Hoosiers have a 64.7% chance to collect the win in this game based on the moneyline’s implied probability. The Ducks have a 39.5% implied probability.
Indiana has compiled a 9-5-0 record against the spread this season.
Oregon has put together an 8-6-0 ATS record so far this season.

Indiana vs. Oregon: 2025 Stats Comparison

	Indiana	Oregon
Off. Points per Game (Rank)	41.6 (2)	38 (6)
Def. Points per Game (Rank)	10.3 (2)	15.1 (10)
Turnovers Allowed (Rank)	8 (3)	12 (16)
Turnovers Forced (Rank)	26 (6)	21 (25)

Indiana 2025 Key Players

Name	Position	Stats
Fernando Mendoza	QB	3,172 YDS (72.3%) / 36 TD / 6 INT 256 RUSH YDS / 6 RUSH TD / 18.3 RUSH YPG
Omar Cooper Jr.	WR	62 REC / 873 YDS / 12 TD / 62.4 YPG
Roman Hemby	RB	1,007 YDS / 7 TD / 71.9 YPG / 5.2 YPC 14 REC / 160 REC YDS / 0 REC TD / 14.5 REC YPG
Elijah Sarratt	WR	54 REC / 703 YDS / 13 TD / 58.6 YPG
Rolijah Hardy	LB	80 TKL / 12 TFL / 8 SACK
Isaiah Jones	LB	58 TKL / 11 TFL / 7 SACK / 1 INT
Aiden Fisher	LB	69 TKL / 5 TFL / 3.5 SACK / 2 INT
Louis Moore	DB	63 TKL / 2 TFL / 5 INT / 5 PD